Few traders and brokers realize that the Letter of Intent is not a standard document in International Trade. When "LOI" is used, it actually refers to the Letter of Indemnity. This is standard usage of the term and has been for decades. The Letter of Intent (hereafter referred to as LOI) is often used in specific domestic trades, such as in real estate or corporate mergers, but it has no standard usage in International Trade itself.
Buyer accepts offer and signs it, where offer acceptance is binding depends of the legal jurisdiction. For example English and common law differs slightly from American uniform commercial law on matters of offer acceptance and when performance becomes binding on an offer. The seller can also reply with a pro forma invoice. In fact a pro forma invoice can serve as quote and offer, becoming a more or less binding purchase order upon buyer acceptance and signing. Pro formas are used more in smaller FCL trades, and not in larger bulk trades.